IRCT20180814040795N2
Recruiting
Phase 3
A comparative study on the effects of oral N-acetylcystein and Pregabalin on the blood level of oxidative stress biomarkers in patients with painful diabetic neuropathy: adouble_blinde randomized clinical trial.
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Hamedan University of Medical Sciences
- Enrollment
- 140
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 30 to 70 years old
- •History of type 2 Diabetes mellitus at least one year ago
- •Hemoglobine A1C Less than or equal to 9
- •Diabetic neuropathy with NDS(Neuropathy Disablity Score) greater than or equal to 6, VAS(Visual analogue scale)fore pain at least 4 and NSS(Neuropathy symptom score) greater than or equal to 5
- •glomerular filtration rate more than 30 cc/min
Exclusion Criteria
- •Type 1 diabetes
- •pregnancy or breastfeeding
- •Diabetic foot ulcer
- •neuropathy for reasons other than diabetes
- •History of cerebrovascular disease and discopathy
- •Use other medications to relieve symptoms of neuropathy
- •Use of alcoholic drink or opioids
Outcomes
Primary Outcomes
Not specified
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