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ow fat versus low carbohydrate weight reduction diets: evaluation of effects on insulin resistance and cardiovascular risk

Completed
Conditions
Obesity
Nutritional, Metabolic, Endocrine
Registration Number
ISRCTN85769730
Lead Sponsor
Royal Group of Hospitals (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
24
Inclusion Criteria

1. Male and female healthy volunteers
2. Aged 18 to 65
3. Body Mass Index (BMI) greater than 27

Exclusion Criteria

1. History of diabetes
2. coronary, hepatic or renal disease
3. Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of insulin sensitivity by hyperinsulinaemic euglycaemic clamp
Secondary Outcome Measures
NameTimeMethod
1. Body weight and composition<br>2. Assessment of blood pressure<br>3. Lipids<br>4. Vascular compliance<br>5. Adiopcykine levels<br>6. Pancreatic funtion
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