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临床试验/CTRI/2024/08/071840
CTRI/2024/08/071840尚未招募4 期

Comparative study of topical minoxidil versus topical minoxidil with dutasteride mesotherapy in androgenetic alopecia A one year hospital based randomized control trial at tertiary care hospital

Dr. Meenal Agrawal1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2024年8月30日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
76
试验地点
1
主要终点
Increased hair density observed trichoscopically

研究概览

简要总结

Although Androgenetic alopecia is often regarded as a rather minor dermatological condition, it affects one’s self-esteem and can be a major source of anxiety and depression for some men.Even while practicing dermatologists and hair specialists deal with it frequently, it might be one of the most difficult conditions to cure because choosing a course of therapy frequently requires careful evaluation of many different aspects as well as ethical decision‐making. The most crucial elements to take into account are treatment cost, practicality in terms of promoting compliance, side effect profiles, and effectiveness—especially in light of the chronic nature of the disease.

While hair transplant surgery is an expensive alternative that may not always provide good results requiring numerous procedures to obtain the necessary hair density, medical treatment for AGA may not be suited for all people and may take a long time to show benefits. Therefore, if mesotherapy with dutasteride turns out to be as effective and safe as the current treatment, it might be a tempting substitute.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 55.00 Year(s)(—)
性别
Male

入选标准

  • Patient with Androgenetic Alopecia confirmed by clinical correlation and trichoscopy.
  • Male Patients belonging to age group of 18-55 years.
  • Patients of Norwood classification grading III,IV,V.
  • Patients with no known comorbidites.

排除标准

  • Norwood classification grading III, VI, VII.
  • Patients with other forms of alopecia Patients with dermatological or systemic illness known to cause diffuse hair loss Patients who received PRP or any hair growth promoters in the past six months Patients who underwent surgical hair transplantation.
  • Patients on hormonal, androgenic or anti androgenic medications, cytotoxic, and inhibitors of CYP3A4 Patients suffering from decreased libido, ejaculatory or erectile dysfunction.

结局指标

主要结局

Increased hair density observed trichoscopically

时间窗: 4 months

次要结局

  • Reduced inter follicular distance observed trichoscopically(4 months)

研究者

发起方
Dr. Meenal Agrawal
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Meenal Agrawal

Jawaharlal Nehru medical college,KLE university

研究点 (1)

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