MIT Intensive Treatment Study

Not Applicable

• Conditions: Aphasia; Motor Speech; Stroke
• Interventions: Behavioral: Melodic Intonation Therapy; Behavioral: Video Feedback Performance Review

• Registration Number: NCT06213376
• Lead Sponsor: Nevada State University

Brief Summary

This study is examining the use of intensive melodic intonation therapy and video feedback as a means of aiding individuals with nonfluent aphasia and co-occurring motor speech impairments. Individuals with nonfluent aphasia have difficulty with language, particularly with word retrieval.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-28
• Status Verified: 2024-01
• Study First Submitted: 2024-01-09
• Study First Submitted QC: 2024-01-09
• Last Update Submitted: 2024-01-09
• Study First Posted: 2024-01-19
• Last Update Posted: 2024-01-19
• Primary Completion: 2024-02
• Study Completion: 2024-06

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• Fluent English speakers
• Sustained a left-hemisphere stroke
• Presents with language and motor speech impairments

Exclusion Criteria

• • History of learning disability prior to accident (per patient report)

  • Uncorrected auditory or visual impairments
  • Not meeting the criteria of stroke
  • Failure to provide evidence of stroke diagnosis (medical record history)
  • History of psychiatric disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Intervention	Melodic Intonation Therapy	20 sessions/4 weeks: Video Feedback: S1) Participant (P1) views recording of previous session with the clinician \& judges whether the production is intelligible. S2) S1 \& the clinician identifies changes in motor movements that are influencing performance. S3+S4) S1+S2 \& given support from the clinician, P1 identifies techniques improving intelligibility \& modifies behavior accordingly. MIT (Albert et al., 1973; Helm-Estabrooks et al., 2014): Humming - Clinician introduces the target phrase by showing a visual cue, humming the phrase, then intoning the phrase while P1 taps left-hand. Simultaneous production with melody - The Clinician and P1 melodically produce the target phrase \& tap together. Simultaneous melodic production accompanied by gradual reduction of clinician support. Immediate repetition response to probe question - Following P1's successful repetition, the clinician melodically produces a question and P1 melodically produces the target.
Intervention	Video Feedback Performance Review	20 sessions/4 weeks: Video Feedback: S1) Participant (P1) views recording of previous session with the clinician \& judges whether the production is intelligible. S2) S1 \& the clinician identifies changes in motor movements that are influencing performance. S3+S4) S1+S2 \& given support from the clinician, P1 identifies techniques improving intelligibility \& modifies behavior accordingly. MIT (Albert et al., 1973; Helm-Estabrooks et al., 2014): Humming - Clinician introduces the target phrase by showing a visual cue, humming the phrase, then intoning the phrase while P1 taps left-hand. Simultaneous production with melody - The Clinician and P1 melodically produce the target phrase \& tap together. Simultaneous melodic production accompanied by gradual reduction of clinician support. Immediate repetition response to probe question - Following P1's successful repetition, the clinician melodically produces a question and P1 melodically produces the target.

Primary Outcome Measures

Name	Time	Method
Intelligibility	From enrollment to 4 weeks post treatment	Intelligibility as measured by percentage of consonants correct and by targets produced on trained and untrained stimuli. 20 trained and 20 untrained speech phrases that are relevant to the client (measured during reading and repetition tasks)

Secondary Outcome Measures

Name	Time	Method
Apraxia Battery for Adults	Baseline and one week following the end of treatment	A test to measure the presence and severity of apraxia in adults
Longer Connected Speech Assessment	Baseline and one and four weeks following the end of treatment	Change in Performance on Rainbow Passage- A public domain paragraph frequently used by speech-language pathologists to gather a speech sample of all phonemes for American English
Assessment of Intelligibility of Dysarthria Speech	Baseline and one week following the end of treatment	A tool for quantifying single-word intelligibility, sentence intelligibility, and speaking rate of adult speakers with dysarthria
Quality of Life with Dysarthria (QOLdys)	Baseline and four weeks following treatments.	A reliable and valid tool to assess quality of life for patients with dysarthria.

Trial Locations

Locations (1)

Nevada State University; 🇺🇸 Henderson, Nevada, United States