A clinical trial to compare the efficacy of intravenous levetiracetam and intravenous phenytoin in control of convulsive status epileptics in children from age group one to twelve years
Phase 4
Completed
- Conditions
- Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes
- Registration Number
- CTRI/2020/01/022641
- Lead Sponsor
- Dr Pooja Shankar Sawlani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 106
Inclusion Criteria
All children from age of one year to 12 years presenting in status epilepticus not controlled by initial emergent therapy with benzodiazepines as per ILAE Protocol.
Exclusion Criteria
1.Status epilepticus controlled by initial emergent therapy with benzodiazepines.
2.Children less than one year of age and >12 years
Received loading dose of second-line anticonvulsants (Phenytoin, Phenobarbitone, Valproate, Levetiracetam) for control of current status epilepticus
3.History of Head injury.
4.Convulsions due to acute metabolic / electrolyte disturbances.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intravenous levetiracetam is superior to intravenous phenytoin in control of convulsions in paediatric populationTimepoint: 24 months
- Secondary Outcome Measures
Name Time Method To provide data regarding decrease incident of recurrence of convulsion while using intravenous levetiracetam in comparison to intravenous phenytoinTimepoint: 1 day