Pre-operative oral supplementation in colorectal cancer patients

Not Applicable

Completed

• Conditions: Colorectal cancer; Cancer; Malignant neoplasm of colon

• Registration Number: ISRCTN02466810
• Lead Sponsor: niversity of Manchester (UK)

Brief Summary

2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28052576

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-23
• Study Completion: 2013-12-30
• Last Update Posted: 1 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 126

Inclusion Criteria

1. Reported weigh loss over the previous 6 months
2. Primary colorectal tumour, eligible for curative surgery
3. Informed consent gained

Exclusion Criteria

1. Pregnant or enrolled in another trial
2. Pacemaker and any metallic implant will preclude individuals from bioelectrical impedance monitoring
3. Cannot give informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of postoperative chest and surgical site infections after CRC surgery, measured from patient medical records reviewed within 30 days after surgery.

Secondary Outcome Measures

Name	Time	Method
<br> As of 17/03/2016:<br> 1. Total complications measured up to 30 days postoperatively<br> 2. Anthropometry<br> 3. Body composition and dietary intake<br> Measured at baseline, 2-3 days preoperatively (where possible) and 7-10 days postoperatively (where possible).<br><br> Initial<br> 1. Anthropometry ? height, weight, body mass index, mid arm circumference (MAC) and skin fold thickness<br> 2. Hand grip strength<br> 3. Co-morbidities<br> 4. 24 hour recalls to assess energy and protein<br> 5. Hospital anxiety and depression score<br> Measured at baseline, 24 hours preoperatively, 7 days post-operatively and at 3 months<br>