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Planned Semi-Elective Lung Transplantation Using 10C Cold Static Preservation

Not Applicable
Completed
Conditions
Pulmonary Disease
Interventions
Procedure: Delayed Lung Transplantation
Procedure: Conventional Lung Transplantation
Registration Number
NCT04568694
Lead Sponsor
NYU Langone Health
Brief Summary

This is a prospective, single-arm study to demonstrate the proof-of-concept of semi-elective lung transplantation. We plan to evaluate 15 patients that receive lung(s) delayed for transplantation under our study criteria.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1
Inclusion Criteria
  • Recipient is ≥ 18 years old
  • Recipient, or their Legally Authorized Representative is able and willing to sign informed consent
  • Recipient meets standard listing criteria for lung transplantation
Exclusion Criteria
  • Donor lungs meet criteria for transplantation with ex vivo lung perfusion (EVLP)
  • Recipient is < 18 years old
  • Recipient, or their Legally Authorized Representative is unable to sign informed consent for re-transplantation
  • Recipient has any condition that, in the opinion of the Investigator, would make study participation unsafe or would interfere with the objectives of the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Delayed Lung TransplantationDelayed Lung TransplantationPatients that received lung(s) delayed for transplantation
Conventional Lung TransplantationConventional Lung TransplantationReference Therapy
Primary Outcome Measures
NameTimeMethod
Incidence of ISHLT primary graft dysfunction grade 3 at 72 hours post-transplant72 hours

As defined by International Society of Heart and Lung Transplantation (ISHLT)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

NYU Langone Health

🇺🇸

New York, New York, United States

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