Measure the levels of inflammatory biomarker(MMP-9)in tooth blood sample for checking the outcome of pulp amputation(pulptomy) procedure in infected tooth.
- Conditions
- Health Condition 1: null- Teeth with symptomatic irreversible pulpitis without periapical pathology
- Registration Number
- CTRI/2018/06/014416
- Lead Sponsor
- Center for Dental Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
1-Healthy patient of either gender belonging to 15-35 years of age group.
2-Mandibular molar teeth with established clinical diagnosis of symptomatic irreversible pulpitis without periapical rarefaction
3-Positive response to cold and electric pulp tests
4-Teeth with restorable carious lesions
1-Teeth with immature roots.
2-Teeth with cracks, cusp fractures, Subgingival caries.
3-Teeth with poor periodontal health, probing pocket depth >3mm, furcation involvement and radiographic horizontal or vertical interdental bone loss.
4-Presence of sinus tract or swelling or periapical pathology on an IOPA radiograph.
5-Patients with systemic conditions which could compromise the healing.
6-Patients not willing to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method higher the levels of MMP-9 in pulpal blood poorer will be the prognosis of pulpotomy procedure in mature teeth with symptomatic irreversible pulpitisTimepoint: 6 months,12 months
- Secondary Outcome Measures
Name Time Method Clinical and radiographic outcome of pulpotomy procedure in teeth with symptomatic irreversible pulpitis.Timepoint: 6 months, 12 months;evaluatation of the correlation between level of MMP-9 in pulpal blood and time required to achieve hemostasis after pulpotomy in teeth with symptomatic irreversible pulpitisTimepoint: after measuring the level of MMP-9 by ELISA test.;Time required to achieve hemostasis after pulpotomy in teeth with symptomatic irreversible pulpitis.Timepoint: immediately at the point of procedure