Changes of Dendritic Cells in Acute Lung Injury

Completed

• Conditions: Acute Lung Injury

• Registration Number: NCT02083393
• Lead Sponsor: Southeast University, China

Brief Summary

To observe changes of circulating and tissue dendritic cells in acute lung injury,including invasive aspergillosis pneumonia

Detailed Description

Change of circulating and tissular dendritic cells of patients with acute lung injury was still unclear, we used a flow cytometry-based assay to quantify circulating and tissular DCs and their HLA-DR surface expression at the time of diagnosis and during the first week of evolution in patients with acute lung injury, and healthy people as controls.

Study Timeline

• Study Start: 2011-06
• Study First Submitted: 2011-09-28
• Study First Submitted QC: 2014-03-07
• Study First Posted: 2014-03-11
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-26
• Last Update Posted: 2015-05-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• Sepsis induced acute lung injury

Exclusion Criteria

• Younger than 18-year-old
• Pregnancy
• Cancer or organ transplant
• Asthma
• COPD
• Heart Failure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28-day mortality	28day

Trial Locations

Locations (1)

Zhongda Hospital Southeast University; 🇨🇳 Nanjing, Jiangsu, China