Tolerance to Light for Patients Suffering From Keratitis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- Light intensity
Study Overview
Brief Summary
In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.
Detailed Description
The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Social security insurance
- •Suspected infectious keratitis (clinically defined. No lab testing required)
- •Signed informed consent
Exclusion Criteria
- •Major Blepharospasm
- •Aphakia (absence of lens)
- •Pregnant woman
- •Nursing mother
Arms & Interventions
Light exposure
The keratitis eye of the patient is exposed to 6 lights with increasing intensity according to a constant speed.
The patients switch off the light when the discomfort is too elevated
Intervention: Light exposure (Device)
Outcomes
Primary Outcomes
Light intensity
Time Frame: At the inclusion
For each wavelength, the highest light intensity tolerated by the patient is measured (mWatts/cm² )
Secondary Outcomes
- Severity of the keratitis(At the inclusion)