NCT07160153招募中不适用
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
University Hospital Pilsen1 个研究点 分布在 1 个国家目标入组 29 人开始时间: 2024年12月3日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 29
- 试验地点
- 1
- 主要终点
- Change in performance TMT-B
研究概览
简要总结
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
详细描述
Evaluate the development of cognitive functions following attainment of abstinence in a group of adolescents with cannabis dependence or harmful cannabis use. Abstinence is confirmed by toxicological testing.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adolescents aged 15-18 years with a diagnosis of cannabis dependence or harmful cannabis use.
排除标准
- •psychiatric comorbidity - Dual diagnosis, including psychotic disorders, mood disorders, severe organic brain damage, or autism spectrum disorder, with the exception of compensated and stabilized anxiety disorder. Psychopharmacological treatment is permitted, except for antipsychotics prescribed for psychosis.
- •somatic comorbidity - Severe endocrine disorders such as diabetes mellitus, thyroid dysfunction, or severe cardiovascular disease.
- •Violation of abstinence between the first and second neuropsychological assessments, as well as severe decompensation of mental state requiring modification of established psychopharmacological treatment.
结局指标
主要结局
Change in performance TMT-B
时间窗: 8 weeks
Change in performance on the Trail Making Test - Part B (TMT-B) \[Time Frame: after 8 weeks of abstinence from cannabis\]
次要结局
- Change in performance on AVLT(8 weeks)
- Change in performance on the Stroop Test(8 weeks)
- Change in performance on the Tower of London(8 weeks)
- Change in performance on CPT-IP(8 weeks)
研究者
研究点 (1)
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