Effect of Vitamin C on Stress in Peritoneal Dialysis Patients
Phase 3
- Conditions
- Peritoneal dialysis patients.End-stage renal disease
- Registration Number
- IRCT2016050227675N2
- Lead Sponsor
- Vice chancellor For Research Of Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion Criteria: Patients treated with peritoneal dialysis for more than six months; Patients with ages: 18-65 years old; Having a regular program of CAPD, three to four times swap by two liters isotonic or hypertonic glucose solution or icodextrin solution for at least 3 months.
Exclusion Criteria
The patients With peritonitis or any other infection at least four weeks before sampling; The incidence of any chronic inflammatory disease; using non-steroidal and allopurinol and antioxidant drugs; Inadequate control of diabetes or HbA1c more than 7.5 %.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Peritoneum and serum total antioxidants capacity (TAC). Timepoint: Before intervention and after completion of intervention in the eighth week. Method of measurement: Venous and peritoneal sampling and sent to the laboratory.;Malonyl dialdehyde (MDA). Timepoint: Before intervention and after completion of intervention in the eighth week. Method of measurement: Venous and peritoneal sampling and sent to the laboratory.
- Secondary Outcome Measures
Name Time Method