EFFECTS OF VITAMIN C ON METABOLISM, OXIDATIVE STRESS AND IMMUNE RESPONSES TO EXERCISE IN PATIENTS WITH DIABETES TYPE II

Phase 1

Completed

• Conditions: type 2 diabetes; fat utilization; immune function; oxidative stress

• Registration Number: TCTR20180226002
• Lead Sponsor: Blackmores

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-04-23
• Study Start: 2018-02-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Age between 45 and 60 years old
2. Being diagnosed as type 2 diabetes mellitus for at least 12 months
3. Hemoglobin A1c more than 8.5%
4. Being treated with oral diabetic drugs only
5. Sedentary and will not participate in any regular exercise program for at least 6 months.
6. Live in Khon Kaen Province, Thailand
7. Vessel state waveform less than level 5

Exclusion Criteria

1. Cardiovascular disease and hypertension
2. Vessel state wave form more than level 5
3. Abnormal resting EKG
4. Blood pressure more than 140/90 mmHg.
5. Orthopedic problems or bone fracture
6. Neuromuscular disorder
7. Liver and kidney disease
8. Chronic infections
9. Autonomic neuropathy
10.VO2,peak less than 10 ml/kg/min

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
metabolism status visit 2,3,5,6 Expired gas collection, miR expression,oxidative stress status visit 2,3,5,6 Blood chem,white blood cell count visit 2,3,5,6 flow cytometry

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A