Efficacy Testing of Crassocephalum Rabens Extract Capsules

Not Applicable

Completed

• Conditions: Aging
• Interventions: Dietary Supplement: Crassocephalum rabens extract

• Registration Number: NCT05309161
• Lead Sponsor: Greenyn Biotechnology Co., Ltd.

Brief Summary

This study is to investigate the improveing effects of the Crassocephalum rebens extract on skin conditions in normal people.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-03
• Study Start: 2022-03-14
• Study First Submitted: 2022-03-16
• Study First Submitted QC: 2022-03-24
• Study First Posted: 2022-04-04
• Primary Completion: 2022-06-30
• Study Completion: 2022-06-30
• Last Update Submitted: 2022-08-01
• Last Update Posted: 2022-08-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Age over 20 years
2. Healthy people

Exclusion Criteria

1. Non-volunteer
2. Pregnant and lactating women
3. Hypersensitivity to the assigned product
4. Diagnosed with skin diseases, liver diseases, kinedy disease, and other severe diseases
5. Cosmetic, drug, or food allergies
6. Concurrent aesthetic treatments (e.g., intense pulse light, medical peelings, or laser therapy)
7. Aceepted aesthetic treatments one month ago before the study
8. Chronic sun exposure (over 3 hours/day)
9. The members of the research team

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A group (placebo)	Crassocephalum rabens extract	Placebo
B group (experimental)	Crassocephalum rabens extract	Crassocephalum rabens extract

Primary Outcome Measures

Name	Time	Method
Measurement of skin texture	Week 4	Visia® skin analysis system is used to measure the skin texture of full face (unit: number of fine lines)
Measurement of skin elasticity	Week 4	Cutometer® is used to measure the skin elasticity of upper cheek (unit: mm)
Measurement of skin spots	Week 4	Visia® skin analysis system is used to measure the skin spots of full face (unit: number of spots)
Measurement of skin hydration	Week 4	Corneometer CM825 is used to measure the moisture of upper cheek (unit: Corneometer® unit)
Measurement of collagen content	Week 4	DermaLab® Series SkinLab Combo (Cortex) is employed to measure skin collagen content of upper cheek (unit: collagen density)
Measurement of skin wrinkles	Weeks 4	Visia® skin analysis system is used to measure the skin wrinkles of full face (unit: number of wrinkles)
Measurement of skin pores	Week 4	Visia® skin analysis system is used to measure the skin spots of full face (unit: number of pores)
Measurement of skin brightness	Week 4	Chroma Meter MM500 is employed to measure the brightness of upper cheek (unit: L\* value (L\* range: 0-100)).
Measurement of Crow's feet	Week 4	Visia® skin analysis system is used to measure the skin spots of full face (unit: number of Visia® skin analysis system is used to measure the skin spots of full face (unit: number of fine lines around eyes)

Trial Locations

Locations (1)

Chia Nan University of Pharmacy ＆ Science; 🇨🇳 Tainan, Taiwan