eural mechanisms of noradrenaline and cortisol effects on memory accuracy vs. generalization over time
Completed
- Conditions
- posttraumatic stress disorder10002861
- Registration Number
- NL-OMON52476
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 112
Inclusion Criteria
Healthy volunteers between 18 and 35 years
Right-handed
Normal uncorrected hearing
Normal or corrected-to-normal vision
Exclusion Criteria
Current regular medication intake (including corticosteroids and adrenergic
medication, monoamine oxidase inhibitors, CYP2D6 inhibitors such as SSRIs)
Pregnancy
Contraindications for MRI scanning (e.g. pacemaker, implanted metal,
claustrophobia)
Current or history of any psychiatric disorder
Disorders of the autonomic system
Cardiovascular or cerebrovascular conditions
Hepatic insufficiency
Renal insufficiency
Glaucoma
Current or history of pheochromocytoma
Recreational drug-use
Smoking
Body mass index lower than 18 or higher than 30
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method