NCT00003571CompletedNot Applicable
Tumor Replication Error (RER) Status and Outcome in a Colon Cancer Adjuvant Chemotherapy Trial
Alliance for Clinical Trials in Oncology44 sites in 1 country300 target enrollmentStarted: August 1998Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 300
- Locations
- 44
- Primary Endpoint
- disease free survival
Study Overview
Brief Summary
RATIONALE: Analyzing the structure of genes found in a person's cancer cells may help doctors improve methods of treating patients with colon cancer.
PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon cancer.
Detailed Description
OBJECTIVES:
- Determine the relationship between disease free survival, overall survival, and tumor replication error status for patients who have received adjuvant chemotherapy for colon cancer on CALGB protocol 8896.
- Determine the prognostic and predictive values for response to this therapy in these patients.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
disease free survival
Time Frame: Up to 10 years
Secondary Outcomes
- overall survival(Up to 10 years)
- tumor replication error status(Up to 10 years)
- determine the prognostic and predictive values for response to this therapy(Up to 10 years)
Investigators
Study Sites (44)
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