Comparative Evaluation of the Efficacy of Vitamin C Tablets in Wound Healing after Surgical Extraction of Mandibular Third Molars-A Split Mouth Randomized Controlled Trial.

This study will include patients indicated for bilateral surgical extraction of mesioangularly impacted mandibular third molar, selected from the Oral and Maxillofacial Surgery OPD. A detailed case history will be recorded, with emphasis on prior allergic reactions to antibiotics, analgesics, vitamin C or citrus fruits. Preoperative evaluation will involve OPG, blood investigation, after obtaining written informed consent. The study follows a split mouth design where each patient serves as both control and study group. Surgical extractions will be performed under Local anaesthesia by a single operator under sterile conditions. Standard post operative instructions will be given and all patients will receive T. Augmentin 625mg BID, T. Diclopara TDS, T. Pan 40 OD for 3 days. Literature indicated no drug interactions between vitamin c and these medications. In control phase no vitamin C supplementation will be prescribed. 1 month later, contralateral tooth will be extracted in an experimental phase during which patient will receive vitamin c chewable tablets TDS for 14days. Follow up will be on post operative day 7 and 14 in both phases. Clinical assessment will include pain evaluation using VAS scale and wound healing using Landry healing index.