NCT03296176Unknown不适用
Metabolomic Study in Huntington's Disease
University Hospital, Angers2 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2017年10月9日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- metabolite mass
研究概览
简要总结
The purpose of this project is to study Huntington's disease by metabolomic approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For all groups:
- •age between 20 and 70 years
- •signature of the informed consent
- •covered by social security
- •For presymptomatic group:
- •positive genetic test with CAG repeat length ≥ 37 in HTT gene
- •Unified Huntington Disease Rating Scale ≤ 5
- •For symptomatic group:
- •positive genetic test with CAG repeat length ≥ 37 in HTT gene
- •The Unified Huntington's Disease Rating Scale motor score ≥ 6
- •The Total Functional Capacity score ≥ 11
排除标准
- •for all groups:
- •participation in another therapeutic trial (3 months exclusion period)
- •pregnancy and breastfeeding
- •persons deprived of their liberty by judicial or administrative decision
研究组 & 干预措施
presymptomatic
Experimental
干预措施: blood sample (Biological)
symptomatic
Experimental
干预措施: blood sample (Biological)
controls
Other
干预措施: blood sample (Biological)
结局指标
主要结局
metabolite mass
时间窗: at baseline
by chromatography and mass spectrometry
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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