NCT06197776招募中不适用
Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for Recurrent and/or Metastatic Nasopharyngeal Carcinoma
Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年7月15日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Failure-free survival
研究概览
简要总结
The observational clinical study will recruit 50 recurrent and/or metastatic nasopharyngeal carcinoma (r/mNPC) patients, to investigate the prediction values of multi-omics technique for the efficacy of chemoradiotherapy combined with immunotherapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recurrent or metastatic nasopharyngeal carcinoma patients
- •All genders，range from 18～70 years old
- •ECOG score 0 ~ 1
- •Inform consent form
排除标准
- •Have or are suffering from other malignant tumors;
- •Participating in other clinical trials;
- •Drug or alcohol addition;
- •Do not have full capacity for civil acts;
- •Mental disorder;
- •Pregnancy or lactation;
- •Severe complication, eg, uncontrolled hypertension.
研究组 & 干预措施
chemoradiotherapy combined with immunotherapy
Patients treated with chemoradiotherapy combined with immunotherapy
干预措施: cisplatin-based chemoradiotherapy combined with immunotherapy (Drug)
结局指标
主要结局
Failure-free survival
时间窗: 3 years
To investigate the multi-omics technique to predict the 3-year failure-free survival of chemoradiotherapy combined with immunotherapy for r/m NPC patients
次要结局
- ctDNA(through study completion, an average of 6 months)
- Tumor mutation load at DNA level(through study completion, an average of 6 months)
- RNA expression(through study completion, an average of 6 months)
研究者
Zhao Chong
Professor
Sun Yat-sen University
研究点 (1)
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