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Prospective Sinonasal Cancer Multi-institution Study

Recruiting
Conditions
Sinonasal Carcinoma
Registration Number
NCT04755855
Lead Sponsor
Mayo Clinic
Brief Summary

This is a multi-institution prospective study of patients with sinonasal malignancies. The goal of this study is to learn more about the course of sinonasal cancer, treatment outcomes, and patient quality of life. In addition, central mutational and genomic analysis of tumor tissue will be evaluated.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Subjects between the ages of 30 days (non-inclusive) and 99 years (inclusive)
  • Patients with a diagnosis of sinonasal cancer
  • Patients undergoing treatment at Mayo Clinic
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Exclusion Criteria
  • Healthy individuals
  • Unwilling to sign the informed consent
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Oncologic outcomes as measured by overall survival, disease specific survival and recurrence free survivalThrough study completion, an average of 5 years
Secondary Outcome Measures
NameTimeMethod
Describe the molecular foundation of sinonasal malignancies utilizing RNA sequencing to identify transcriptomic tumor profilesThrough study completion, an average of 5 years
Quality of life outcomes including the University of Washington Quality of Life Questionnaire (UW-QOL v4) and the Sinonasal Outcome Test 22 (SNOT22)Through study completion, an average of 5 years

Trial Locations

Locations (1)

Mayo Clinic in Rochester

🇺🇸

Rochester, Minnesota, United States

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