Multicenter Prospective Randomized Trial Comparing Standard Esophagectomy With Chemoradiotherapy for Treatment of Squamous Esophageal Cancer: Early Results From the Chinese University Research Group for Esophageal Cancer (CURE)

Chinese University of Hong Kong0 sites40 target enrollmentJuly 2000

ConditionsEsophageal Cancers

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Esophageal Cancers
Sponsor: Chinese University of Hong Kong
Enrollment: 40
Primary Endpoint: Overall survival and disease-free survival
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The aim of this study is to compare outcomes in patients with operable squamous carcinoma of the esophagus who have received either surgery or definitive chemoradiation (CRT).

Registry

clinicaltrials.gov

Start Date

July 2000

End Date

June 2009

Last Updated

16 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Chinese University of Hong Kong

Eligibility Criteria

Inclusion Criteria

•Eligible patients had mid or lower thoracic esophageal cancers that were confirmed on histology to be a squamous cell carcinoma deemed to be resectable.

Exclusion Criteria

•The investigators excluded those patients who had distant metastasis to solid visceral organs or local invasion into trachea, descending aorta, or recurrent laryngeal nerve.
•Those patients who were older than 75 years or who had a serious premorbid condition or a poor physical status that compromised a thoracotomy were also excluded.