ISRCTN40935649已完成4 期
Inflammatory response in major injury and recombinant human erythropoietin
Abertawe Bro Morgannwg University Health Board0 个研究点目标入组 400 人开始时间: 2016年3月17日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged between 18-60 years
- •2. Blunt trauma patients admitted to ITU
- •3. Injury severity score (ISS) at least 16
- •4. ITU stay expected to last at least 3 days
排除标准
- •1. Pregnancy (an admission pregnancy test is routine in all female trauma patients who are of child-bearing age)
- •2. Presence of a severe isolated traumatic brain injury
- •3. Presence of any blood-borne infections e.g. HIV, hepatitis B or C.
- •4. Presence of any known malignancies
- •5. Presence of not been consented by a personal legal representative or a professional legal representative if the former is not available
- •6. Are already participating in another clinical trial
- •7. Presence of a contra-indication to thromboprophylaxis
- •8. Presence of contra-indications for rhEPO:
- •8.1. Uncontrolled hypertension
- •8.2. Known sensitivity to mammalian cell derived products
- •8.3. Hypersensitivity to the active substance or to any of the excipients
- •8.4. Severe coronary, peripheral arterial, carotid or cerebral vascular disease, including patients with recent myocardial infarction or cerebral vascular accident
- •8.5. Patients who have developed Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
- •8.6. A history of thrombo-embolic vascular (TVE) events
研究者
相似试验
进行中（未招募）
1 期
Can artificially made human erythropoietin improve recovery after major injuries?EUCTR2015-002255-10-GBAbertawe Bro Morgannwg University Health Board10
已完成
不适用
Acute and chronic inflammatory responses induced by smoking in individuals being susceptible and non-susceptible for development of COPD: from specific disease phenotyping towards novel made therapy (study 1).chronic ibstructive brochitis( COPD)10010613emphysemaNL-OMON31923niversitair Medisch Centrum Groningen120
已完成
不适用
Acute and Chronic inflammatory responses induced by smoking in individuals being susceptible and non-susceptible for development of COPD: from specific disease phenotyping towards novel therapy (study 2).chronic obstructive bronchitis (COPD)10046304emphysemaNL-OMON32401niversitair Medisch Centrum Groningen300
终止
不适用
Polytrauma and Resuscitation Impact on Innate ImmunityWounds and InjuriesNCT06314841Ludwig Boltzmann Gesellschaft62
已完成
不适用
Histological Evaluation and Inflammatory Response of Different Abutment Materials: An Experimental Study in Humaedentulous space at posterior areano grafting neededenough width of attach gingivaTCTR2016041100390th Anniversary of Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund)15