EaStER: Early Stage glottic laryngeal cancer: Endoscopic excision or Radiotherapy? - a feasibility study

Completed

• Conditions: Cancer; Early stage glottic cancer; Head and neck cancer

• Registration Number: ISRCTN17541410
• Lead Sponsor: niversity College London (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-06-22
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Histologically confirmed squamous cell carcinoma of the glottic larynx, including tumours at the anterior commisure
2. Stage Tis, T1, T2a, N0, M0
3. Anatomy of airways suitable for endoscopic excision
4. Fit to receive radical treatment as either radiotherapy or endoscopic excision
5. Age 18 years or greater
6. Willing to participate in a recruitment appointment
7. Willing to complete voice and quality of life questionnaires
8. Available for follow up within the UK

Exclusion Criteria

1. Any clinical or radiological sign of nodal involvement
2. Any evidence of clinical metastases
3. Any previous cancer within 10 years (except basal cell carcinoma of the skin and adequately treated carcinoma-in-situ of the uterine cervix)
4. Concomitant chemotherapy
5. Patients with vasculitic conditions adversely affecting radiotherapy
6. Pregnancy
7. Other co-existing medical condition such that life expectancy is less than two years
8. Treatment with palliative intent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ot provided at time of registration

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration