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Clinical Trials/NCT03304366
NCT03304366
Unknown
Not Applicable

The Use of Pentacam in Assessment of Corneal Changes After Pterygium Excision

Assiut University0 sites30 target enrollmentNovember 2017
ConditionsPterygium

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pterygium
Sponsor
Assiut University
Enrollment
30
Primary Endpoint
Pentacam analysis.
Last Updated
8 years ago

Overview

Brief Summary

Aim of this study is to assess the corneal changes before and after pterygium excision by using pentacam system.

Detailed Description

Pterygium is a dysplasia of the bulbar conjunctiva extending onto the corneal surface. The prevelance of pterygium ranges from 0.7% to 31% in various populations according to the location, altitude, and race. It has a higher prevelance in areas which have increased exposure to direct sun with ultraviolet (UV) B light. Patients with pterygia present with variety of complaints ,ranging from asymptomatic to significant redness ,swelling ,itching ,irritation and blurring of vision associated with elevated lesions of the conjunctiva and contiguous cornea in one or both eyes.The induction of astigmatism due to the invasion of the pterygium into the cornea as well as changes in corneal curvature and refractive status has been reported by numerous studies. Multiple different procedures have been advocated in the treatment of pterygia. These procedures range from simple excision to sliding flaps of conjunctiva with or without adjunctive external beta radiation therapy and/or use of topical chemotherapeutic agents, such as Mitomycin C. Pentacam is a rotating Scheimpflug camera which measures Scheimpflug images of the anterior eye segment. With the pentacam, topographic analysis of the corneal front and back surfaces is based on the true elevation measurement from one side of the cornea to the other (limbus to limbus). Pentacam also describes the true thickness of the cornea across its entire breadth and width. Type of the study: prospective observational longitudinal study Study Setting: Assuit University Hospital ( ophthalmology Department ) Assuit Police Hospital ( ophthalmology Department ) Study subjects: 1. Inclusion criteria: * The study will include 30 eyes of adult subjects. * All eyes have primary pterygium and seeking for surgery due to Cosmetic problems, ocular irritation, and, or visual impairment. * All selected patients will undergo complete ophthalmological examination including refraction, best corrected visual acuity, keratometry, and pentacam (scheimpflug imaging) preoperatively then will be followed up 2 and 6 months post pterygium excision. 2. Exclusion criteria: * patients with recurrent pterygium. * Patients with media opacities: * Dense cataract. - Corneal opacities. * Patients with a history of intraocular surgery ,ocular trauma ,and contact lens wear. * Patients with severe ocular surface disorders as Stevens-Johnson syndrome.

Registry
clinicaltrials.gov
Start Date
November 2017
End Date
January 2019
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohamed Gamal

Resident Physician

Assiut University

Eligibility Criteria

Inclusion Criteria

  • All eyes have primary pterygium and seeking for surgery due to Cosmetic problems, ocular irritation, and, or visual impairment.
  • All selected patients will undergo complete ophthalmological examination including refraction, best corrected visual acuity, keratometry, and pentacam (scheimpflug imaging) preoperatively then will be followed up 2 and 6 months post pterygium excision.

Exclusion Criteria

  • patients with recurrent pterygium.
  • Patients with media opacities: Dense cataract, Corneal opacities.
  • Patients with a history of intraocular surgery ,ocular trauma ,and contact lens wear.
  • Patients with severe ocular surface disorders as Stevens-Johnson syndrome.

Outcomes

Primary Outcomes

Pentacam analysis.

Time Frame: preoperative and then will be followed up 2 and 6 months post pterygium excision.

Corneal changes such as thickness and elevations

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