Comparison Between Bare Scleral Technique and Conjunctival Auto-graft on Corneal Topography After Pterygium Surgery

Not yet recruiting

• Conditions: Corneal Topography
• Interventions: Device: corneal topography

• Registration Number: NCT05812508
• Lead Sponsor: Sohag University

Brief Summary

Aim of the work:

To study the corneal topographic pattern changes in patients who have pterygium excision by two surgical techniques (bare sclera, conjunctival autograft).

Detailed Description

Pterygium is one of the common ocular surface disorders , it's is an elastotic triangular fibro-vascular tissue covered by conjunctival epithelium that spreads over the cornea. Pterygium causes differences in curvature \& power across the cornea .

The prevalence of pterygium varies from 1.1% to 53% globally in different environmental conditions. Risk factors include;UV radiation, geographical latitude near to the equator, outdoor activity , aging, male, and dusty environment.

Pterygium excision is important in patients suffering from blurred vision due to astigmatism . Surgical techniques include ; bare sclera excision, conjunctival autograft, conjunctival transpositional flap, and amniotic membrane grafting. Pterygium excision increases in the mean central corneal curvature \& reduces astigmatism that leads to improvement in visual acuity.

Corneal topography is a gold standard in corneal pathology follow-up. Corneal topography is a computer assisted diagnostic tool that creates a three-dimensional map of the surface curvature of the cornea. Corneal topography produces a detailed, visual description of the shape and power of the cornea.

In this study , corneal topography is used to detect how does corneal curvature change after excision of pterygium .

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study First Submitted: 2023-03-04
• Status Verified: 2023-04
• Study First Submitted QC: 2023-04-02
• Last Update Submitted: 2023-04-02
• Study First Posted: 2023-04-13
• Last Update Posted: 2023-04-13
• Study Start: 2023-04-20
• Primary Completion: 2023-08-01
• Study Completion: 2023-10-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients with pterygium not associated with other pathologies (suitable for excision).
• Nasal pterygium extended to the cornea.

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Exclusion Criteria

• Associated pathologies such as glaucoma, and cataract.
• Corneal opacities or irregularities, scars, dystrophy or ectasia.
• Patients who underwent previous corneal surgery (including refractive surgery)
• Pseudo-pterygium.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
pterygium surgery with bare scleral technique	corneal topography	corneal topograghy before and after surgery
pterygium surgery with conjunctival autograft technique	corneal topography	corneal topograghy before and after surgery

Primary Outcome Measures

Name	Time	Method
comparison of topography finding after pterygium surgery by the bare scleral technique.	baseline	To investigate the corneal topographic changes by imaging the corneal topography before and after pterygium excision (by the bare scleral technique); to detect corneal curvature changes.
comparison of topography finding after pterygium surgery by the conjunctival auto-graft technique.	baseline	To investigate the corneal topographic changes by imaging the corneal topography before and after pterygium excision (by the conjunctival auto-graft technique); to detect corneal curvature changes.