Effect of vitamin D supplementation on muscle mass and function among sarcopenic elderly adults with vitamin D insufficiency: a randomized controlled trial
Not Applicable
Completed
- Conditions
- sarcopenia
- Registration Number
- JPRN-UMIN000048060
- Lead Sponsor
- Tianjin Medical University,Nutrition and epidemiology ins titution
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 226
Inclusion Criteria
Not provided
Exclusion Criteria
(1) taking vitamin D supplements. (2) participants with severe depression, cognitive impairment, cardiovascular and cerebrovascular diseases (stroke and myocardial infarction), cancer, impaired hepatic function, impaired renal function, and other serious metabolic diseases. (3) unable to complete the follow-up.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways does vitamin D supplementation modulate to improve muscle mass in sarcopenic elderly with vitamin D insufficiency?
How does vitamin D supplementation compare to resistance training in enhancing muscle function among sarcopenic patients with vitamin D deficiency?
Which biomarkers, such as serum 25(OH)D or VDR gene polymorphisms, correlate with response to vitamin D in sarcopenia trials?
What adverse events are associated with high-dose vitamin D supplementation in elderly sarcopenia patients, and how are they managed?
Are combination therapies of vitamin D with anabolic agents or protein supplements more effective than monotherapy for sarcopenia in vitamin D-insufficient elderly?