The Effect of Liquorice on Plasma Potassium

Not Applicable

Terminated

• Conditions: Healthy
• Interventions: Other: Liquorice 66 g/day; Other: Liquorice 102 g/day

• Registration Number: NCT00927017
• Lead Sponsor: University of Oulu

Brief Summary

The hypothesis is that liquorice lowers plasma potassium. This study aims to elucidate the dose-response of this effect with two doses of liquorice (66 grams or 102 grams) per day for two weeks.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06
• Study First Submitted: 2009-06-22
• Study First Submitted QC: 2009-06-23
• Study First Posted: 2009-06-24
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2010-04
• Last Update Submitted: 2010-04-06
• Last Update Posted: 2010-04-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• healthy volunteers
• age 18-40

Exclusion Criteria

• any continuous medication
• hypertension or hypotension
• allergy to liquorice
• pregnancy or lactation
• difficult venipuncture
• drug or alcohol abuse
• participation in pharmaceutical trial

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Liquorice 66 g/day	Liquorice 66 g/day	Liquorice given 66 grams per day for two weeks
Liquorice 102 g/day	Liquorice 102 g/day	Liquorice given 102 grams per day for two weeks

Primary Outcome Measures

Name	Time	Method
Change in plasma potassium	1 week, 2 weeks

Trial Locations

Locations (1)

Oulu University Hospital; 🇫🇮 Oulu, Finland