Association Between Time From PCI to Cancer Surgery and Cardiovascular and Oncologic Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,621
- 主要终点
- Occurence of Bleeding
研究概览
简要总结
To evaluate the association between time from PCI to cancer surgery and cardiovascular and oncologic outcomes in early-stage cancer patients, A retrospective, population-based cohort study was conducted using data from the Korean National Health Insurance Service (K-NHIS) database.
详细描述
Early-stage-cancer patients with a history of PCI who underwent cancer surgery (N = 3621) were included. The patients were divided into two groups based on the time between the dates of PCI and cancer surgery (<12 months and ≥12 months). Patients were stratified into early-surgery and late-surgery, defined as patients who underwent surgery ≥1 and <1 month after cancer diagnosis. Outcomes included bleeding, spontaneous myocardial infarction (MI), repeat revascularization, cancer recurrence, and death.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •men and women aged ≥18 years who were diagnosed with cancer and underwent cancer surgery within 1 year following diagnosis.
- •patients who underwent PCI (procedure code: M6551-M6572, O1640-O1649, OA640-OA649) prior to the cancer surgery
排除标准
- •participants who received neoadjuvant or adjuvant treatment for cancer
结局指标
主要结局
Occurence of Bleeding
时间窗: up to 5 years
Bleeding requiring transfusion was defined by the transfusion codes (X2021, X2022, X2031, X2032, X2091, X2092, X2111, X2112, X2131, X2132).
次要结局
- Occurence of All cause death(up to 5 years)
- Occurence of Cancer recurrence(up to 5 years)
- Occurence of Repeat revascularization(up to 5 years)
- Occurence of Spontaneous myocardial infarction(up to 5 years)
研究者
Ki Hong Choi
Professor
Samsung Medical Center