Gastric emptying and digestion of whey protein gels
- Conditions
- digestive physiology
- Registration Number
- NL-OMON20045
- Lead Sponsor
- Wageningen University & Research
- Brief Summary
Deng, R., Janssen, A. E. M., Vergeldt, F. J., Van As, H., de Graaf, C., Mars, M., & Smeets, P. A. M. (2020). Exploring in vitro gastric digestion of whey protein by time-domain nuclear magnetic resonance and magnetic resonance imaging. Food Hydrocolloids, 99. http://doi.org/10.1016/j.foodhyd.2019.105348
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
•18-45 years old
•Male
•Apparently healthy (self-reported)
•Healthy body weight, BMI 18.5 - 25 kg/m2
•Able to speak and understand English without difficulty
•Vegan
•Whey protein allergy or intolerance (self-reported)
•Food sensitivities towards any of the ingredients
•Gastric disorders or regular gastric complaints, such as heart burn
•Use of proton pump inhibitors or other medication which alters the normal functioning of the stomach
•Having a contra-indication to MRI scanning (including, but not limited to):
Pacemakers and defibrillators
Intraorbital or intraocular metallic fragments
Ferromagnetic implants
Claustrofobia
•Participating in any other medical-scientific research
•An employ from Human Nutrition and Health (WUR)
•A student or intern from Chair of Sensory Science and Eating Behaviour (WUR)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary: Gastric emptying half-time measured by MRI.
- Secondary Outcome Measures
Name Time Method Secondary: Protein hydrolyses will be quantified by MRI T1 and T2 during digestion.