Midtrimester preterm prelabour rupture of membranes (PPROM). Expectant management or Amnioninfusion for improving perinatal outcomes.

Academical Medical Centre Amsterdam0 sites56 target enrollmentTBD

ConditionsPerinatal mortality. The number of stillbirths and deaths in the first week of life.Perinatale sterfte. Het aantal doodgeborenen en doden in de eerste levensweek.Keywords: Midtrimester preterm prelabour rupture ofmembranes. Perinatal outcome. Oligohydramnios. Amnioinfusion.

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Perinatal mortality. The number of stillbirths and deaths in the first week of life.Perinatale sterfte. Het aantal doodgeborenen en doden in de eerste levensweek.Keywords: Midtrimester preterm prelabour rupture ofmembranes. Perinatal outcome. Oligohydramnios. Amnioinfusion.
Sponsor: Academical Medical Centre Amsterdam
Enrollment: 56
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

last year

Study Type

Interventional

Investigators

Sponsor

Academical Medical Centre Amsterdam

Eligibility Criteria

Inclusion Criteria

•Women with a singleton pregnancy complicated by oligohydramnios secondary to PPROM at a gestational age between 16 and 24 weeks, minimum 72 hours after PPROM was diagnosed, but no longer than 21 days after this diagnosis.

Exclusion Criteria

•Women having signs of premature uterine contractions, intra uterine infection, or wornen having a maternal disease (hypertension, HELLP syndrome, preeclampsia or other) as reason for delivery. Placental or major structural fetal anomalies. Signs of cervical incompetence. Women whose child has signs of fetal distress (abnormal biophysical profile).

Outcomes

Primary Outcomes

Not specified

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