MedPath

Effects of Transcranial Direct Current Stimulation (tDCS) over Craving in abstinence methamphetamine user

Phase 2
Conditions
Methamphetamine dependency.
Dependence syndrom, Mental and behavioural disorders due to use of other stimulants, including methamphethamine
Registration Number
IRCT2012102311234N1
Lead Sponsor
Vice Chancellor for Research,Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Male
Target Recruitment
32
Inclusion Criteria

Inclusion Criteria;
Having a history of at least 12 months methamphetamine dependence, based on DSM-IV-TR criteria; before entering the treatment program and also being abstinence from any drugs except cigarettes, at least for the last week; We tested subjects’ cue-reactivity in the recruitment process based on their subjective reports of craving feeling after exposure to 2 drug-related cues, which were not included in the main craving task; Subjects were excluded if at least their mean craving self-report was below 20 out of 100.

Exclusion Criteria

Individuals with any current or past clinical significant neurologic disorder; usage of central nervous system-effective medication; history of epilepsy; brain surgery;tumor; intracranial metal implantation; clinically significant head trauma; or any clinical significant psychiatric disorder (in axis I, except substance-related disorders).

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Methamphetamine Craving. Timepoint: before intervention, online with intervention and After intervention. Method of measurement: Computerized Cue-induced Craving Assessment Task(CCIC), Desires for Drug Questionnaire (DDQ).
Secondary Outcome Measures
NameTimeMethod
Mood Status. Timepoint: It is assessed before and after brain stimulation and induced craving, in both sessions. Method of measurement: Positive and Negative Affect Scale(PANAS).
© Copyright 2025. All Rights Reserved by MedPath