Does the combination of ventilator waveforms and diaphragm and intercostal EMG improve the identification of patient-ventilator-asynchrony in mechanically ventilated children compared with waveforms alone?

Completed

Conditions: Ventilator interaction
10024967

Registration Number: NL-OMON47162

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 83

Inclusion Criteria

Mechanically ventilated children who are able to trigger the ventilator aged 0-18 years.

Exclusion Criteria

-premature birth with gestational age corrected for post-conceptional age less than 40 weeks
-congenital or acquired neuromuscular disorders
-congenital or acquired central nervous system disorders with depressed respiratory drive
-severe traumatic brain injury (i.e. Glasgow Coma Scale < 8)
-congenital or acquired damage to the phrenic nerve
-congenital or acquired paralysis of the diaphragm
-use of neuromuscular blockade
-chronic lung disease
-severe pulmonary hypertension

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary objective is to compare the incidence of<br /><br>patient-ventilator-asynchrony during paediatric mechanical ventilation using<br /><br>ventilator waveforms with PVA detected by using the ventilator waveforms in<br /><br>combination with diaphragm and intercostal EMG.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Level and time course of incidence PVA.<br /><br>-Time course of distribution of type of PVA.<br /><br>-Level and time course of diaphragm EMG.<br /><br>-Level and time course of intercostals EMG.<br /><br>-Level and time course of phase angle distribution.<br /><br>-Effect of imposed work of breathing on incidence PVA.</p><br>