Comparison of modes of ventilation in spine surgery in prone position.
Phase 4
- Conditions
- Health Condition 1: D334- Benign neoplasm of spinal cordHealth Condition 2: S320- Fracture of lumbar vertebraHealth Condition 3: S220- Fracture of thoracic vertebraHealth Condition 4: C720- Malignant neoplasm of spinal cordHealth Condition 5: S331- Subluxation and dislocation of lumbar vertebra
- Registration Number
- CTRI/2019/08/020811
- Lead Sponsor
- Department of Anaesthesiology and Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients aged 18 to 60 years, of either sex, belonging to ASA physical status I â?? II scheduled to undergo thoracolumbar spine surgery (for tumors or trauma) in prone position under general anesthesia will be enrolled in the study.
Exclusion Criteria
Patients having Bronchopulmonary disease (like asthma, chronic bronchitis, emphysema), Cardiac disease, BMI >30 kg/m2, Cerebrovascular disease, Neuromuscular disorder and Multiple trauma will be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Respiratory mechanics (peak airway pressure, plateau pressure, lung compliance, dead space and oxygenation). <br/ ><br> <br/ ><br>2. Pulmonary function tests (Vital capacity, Peak expiratory flow rate, forced expiratory volume in first second).Timepoint: Respiratory mechanics will be assessed for both pressure control and volume control ventilation intraoperatively. PFTs will be done preoperatively the same day as baseline, intraoperatively and one day postoperatively only. The above data will be compiled and appropriate statistical test will be used to analyse the results.
- Secondary Outcome Measures
Name Time Method Haemodynamic parameters (Heart rate, blood pressure, SpO2)Timepoint: The above outcome will be assessed for both pressure control and volume control ventilation intraoperatively only. Data will be compiled and appropriate statistical test will be used to analyse the results.