The short-term effect of glucose and sacharose ingestion on cognitive performance and mood in elderly subjects
Completed
- Conditions
- cognitive performancemental health10013511
- Registration Number
- NL-OMON36126
- Lead Sponsor
- De Suikerstichting Nederland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 42
Inclusion Criteria
Elderly women and men >= 70 years
Memory complaints
Able to understand and perform study procedure
Exclusion Criteria
• Type I or type II diabetes (fasted blood glucose level >= 7,0 mmol)
• Parkinson disease
• MMSE < 25 (to exclude cognitively impaired subjects)
• CES-D score > 16 (to exclude depressive subjects)
• Pharmacological antidepressiva or medication for dementia
• Liver disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome will be the difference in memory after the glucose drink<br /><br>and the sacharose drink versus the placebo drink. Different sensitive memory<br /><br>tests will be used. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Next to the effect of glucose and sacharose on memory, the effect on attention<br /><br>will be measured by performing a high-demanding attention task. Furthermore,<br /><br>mood will be assessed by the POMS-questionnaire. Blood glucose response will be<br /><br>determined, even as blood levels of insulin. </p><br>