Clinical efficacy of Rong-Yang-Jyh-Gan-Tang on patients with chronic hepatitis C: a double-blinded randomized placebo-controlled cross-over study

Recruiting

• Conditions: chronic hepatitis C; Alternative and Complementary Medicine - Herbal remedies; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12613000229774
• Lead Sponsor: Commitee on Chinese Medicine and Pharmacy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-02-27
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Chronic hepatitis C patients are older than twenty years old; Anti-HCV reaction is positive.
2. HCV RNA load is positive (greater than 15IU/ml), Alanine Aminotransferase (ALT) is greater than the standard value(40U / L).
3. Had failed in receiving the standard interferon-based treatment (including non-response and recurrence), or are not candidates for interferon treatment for hepatitis C patients.

Exclusion Criteria

1. Patients had symptoms of acute diarrhea over the past two weeks.
2. Pregnant women or breastfeeding women.
3. Patients had compensatory disorders of liver disease or liver cirrhosis, such as esophageal variceal bleeding, ascites, hepatic encephalopathy, bilirubin greater than 2.0mg/dl and spontaneous bacterial peritonitis over the past six months.
4. Liver cancer or other treatment in malignant tumor.
5. Combined hepatitis B virus or HIV infection.
6. Drug or alcohol abuse.
7. Having allergies in Traditional Chinese medicine preparation.
8. Serious systemic diseases, such as severe cardiopulmonary disease or illness which will affect clinical research proceeding and evaluation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified