Evaluation the effect of melatonin on tourniquet pai

Phase 2

• Conditions: Pain.; Pain in arm, unspecified; M79.603

• Registration Number: IRCT20160430027677N9
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients aged 20-60 years
Patients with American Society of Anesthesiologists (ASA) physical status classification I–II
Elective upper limb surgery
Surgery with intravenous regional anesthesia

Exclusion Criteria

Raynaud’s disease
Sickle cell anemia
Chronic pain syndromes
Depression or schizophrenia
Epilepsy
Leukemia
Autoimmune disease
Diabetes
Those who used any analgesic or sedative 24h before surgery
Those with allergy to any of the study medications
Pregnants
Breast-feeding women

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Verbal Pain Score.;Anxiety. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Verbal Anxiety Score.

Secondary Outcome Measures

Name	Time	Method
Mean arterial pressure. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: None invasive barometer pressure.;Heart rate. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Electrocardiogram.;Arterial oxygen saturation. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Pulse oximeter.