Pathophysiology of respiratory muscle involvement in lung transplant recipients

• Conditions: Z94.2; J44.9; Lung transplant status; Chronic obstructive pulmonary disease, unspecified

• Registration Number: DRKS00015912
• Lead Sponsor: Institut für Schlafmedizin und neuromuskuläre Erkrankungen, Universitätsklinikum Münster

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-16
• Study Completion: 2019-02-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

a. Age > 18 years (no age limit)
b. able to consent
c. chronic lung disease with lung transplantation

Exclusion Criteria

- other severe internistic pre-existing conditions, especially insulin-dependent diabetes or severe endstage renal impairment
- severe neurological pre-existing conditions, especially brainstem infarction
- intake of opioids
- severe psychiatric pre-existing conditions

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Twitch transdiaphragmatic pressure after magnetic cervical stimulation of the phrenic nerves [cmH2O]