Standardized training for improvement of the musculoskeletal unit and for prevention of falls and fracture in the elderly: a prospective randomized controlled trial. Age adjusted impact strength and enDurance training in Osteoporotic patients - Novel structu-red Intervention in Seniors (the Rostocker ADONIS-Trial)

Phase 1

• Conditions: M80-M85; Disorders of bone density and structure

• Registration Number: DRKS00009890
• Lead Sponsor: Klinik für Unfall-, Hand-, und Wiederherstellungschirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-07-31
• Study Start: 2016-01-22
• Results First Posted: 2016-12-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

age = 65 years, T-score = - 2.5 standard deviation at the lumbar spine and/or femoral neck (measurement of BMD at max. 36 months prior to enrolment) or a history of osteoporotic fractures, walking speed = 0.8 m·s-1, chair rising test = 10 s, body mass index = 20 kg/m2, increased risk of falls and fractures, i.e. at time of enrolment at least one fall during the last 12 months.

Exclusion Criteria

active participation in a strength and/or endurance training during a 24-months period prior to enrolment, sports activity = two times a week, cardiac insufficiency, cardiac pacemaker, chronic renal failure, non-curative treated tumours, systemic application of corticosteroids, peripheral arterial occlusive disease, poor mobility, i.e. walking more than 5 min not possible, osteoarthritis, rheumatism and/or severely impaired balance, planed absence of more than two weeks during the study period

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
feasibility of the training<br>acceptance of intensity and frequence<br>Questionaires (QUALEFFO-41, FES-1) at time of enrollment (baseline) and after 3 and 6 months of training

Secondary Outcome Measures

Name	Time	Method
improvement of muscular function (power) by 10% within 6 months of training<br>Questionaires, assessment of endurance and power at time of enrollment (baseline) and after 3 and 6 months of training