A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)

Not Applicable

Active, not recruiting

• Conditions: COPD; Asthma

• Registration Number: NCT03927820
• Lead Sponsor: Vanderbilt University Medical Center

Brief Summary

The goal of this study is to assess the impact of pharmacist-led benefits investigations and application of clinical practice guidelines on patient access to inhalers and time to hospital readmission or Emergency Department (ED) visit.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-04-23
• Study First Submitted QC: 2019-04-23
• Study First Posted: 2019-04-25
• Study Start: 2019-09-09
• Status Verified: 2025-08
• Last Update Submitted: 2025-08-22
• Last Update Posted: 2025-08-29
• Primary Completion: 2026-06
• Study Completion: 2026-06-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 914

Inclusion Criteria

• Adult patient admitted to Vanderbilt University Medical Center (VUMC) (excluding surgery services)
• on a long acting inhaler or prescribed a long acting inhaler during admission.

Exclusion Criteria

• Diagnosis of cystic fibrosis
• Diagnosis of graft versus host disease (GVHD)
• no medication insurance
• discharge to any post-acute care facility or inpatient hospice
• death during hospitalization

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Time to either hospital readmission or ER visit	6 months	Combined time (days) to either hospital readmission or emergency department visit after hospitalization (all outcomes measured at 6 months post-discharge with a 3 month interim analysis)

Secondary Outcome Measures

Name	Time	Method
frequency of prescribed inhaler at discharge	6 months	number of times the recommended inhaler was prescribed at discharge
frequency of hospital readmissions	6 months	number of hospital readmission 6 months post-discharge
frequency of short course prescription of oral steroid	6 months	number of oral steroid prescriptions in the 6 months post-discharge
Frequency of ED visit	6 months	number of ED visits 6 months post-discharge
time to 1st ED visit (days)	6 months	time until the first ED visit post-discharge
time to 1st readmission (days)	6 months	time until the first readmission post-discharge

Trial Locations

Locations (1)

Vanderbilt Univeristy Medical Center; 🇺🇸 Nashville, Tennessee, United States