Metabolic Syndrome Cohort in Korea
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Cardiovascular events
研究概览
简要总结
Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey. Enrolled patients will have coronary CT, 2D echocardiogram, treadmill test, pulse wave velocity, augmentation index, carotid intima-media thickness, and abdominal fat mass evaluation. Moreover, lipid profiles and inflammatory markers such as hsCRP, IL-6, TNF-alpha, VCAM-1, ICAM-1, adiponectin, MMP-9 will be measured. All participants will repeat the test and survey every year in Korea University Hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •3 out of 5 criteria
- •Central obesity: Men ≥ 90 cm Women ≥ 85 cm
- •Plasma triglycerides ≥ 150 mg/dL
- •HDL cholesterol Men < 40 mg/dL, Women < 50 mg/dL
- •Blood pressure ≥130/85 mm Hg (or treatment for hypertension)
- •Fasting plasma glucose ≥ 100 mg/dL
- •Age between 30 to 64
- •Consent to our registry protocol
排除标准
- •Patients who could not undergo coronary CT, 2D echocardiogram, treadmill test, and pulse wave velocity.
结局指标
主要结局
Cardiovascular events
时间窗: 10 years
Cardiovascular events such as fatal and non-fatal myocardial infarction, heart failure, need for coronary and peripheral revascularization, stroke, all-cause death, and cardiac death.
次要结局
未报告次要终点
研究者
Soon Jun Hong
Associate Professor
Korea University Anam Hospital