Studying Gene Expression and Location in Samples From Patients With Brain Tumors
Completed
- Conditions
- Brain and Central Nervous System Tumors
- Registration Number
- NCT01585389
- Lead Sponsor
- Children's Oncology Group
- Brief Summary
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to brain tumors.
PURPOSE: This research studies gene expression and location in samples from patients with brain tumors.
- Detailed Description
OBJECTIVES:
* To determine the expression and subcellular localization of nei endonuclease VIII-like 3 (NEIL3) in brain tumors.
OUTLINE: Tissue microarray samples are analyzed for NEIL3 expression and subcellular localization by immunohistochemical methods.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of NEIL3 expression and/or nuclear localization with tumor type or grade with respect to degree of differentiation
- Secondary Outcome Measures
Name Time Method