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Clinical Trials/NCT04281225
NCT04281225
Withdrawn
N/A

Mindfulness Intervention and Symptom Variability in Hearing

Harvard University1 site in 1 countryNovember 1, 2021
ConditionsHearing Loss

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hearing Loss
Sponsor
Harvard University
Locations
1
Primary Endpoint
Hearing Change - subjective preferred volume
Status
Withdrawn
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this study is to investigate the efficacy of mindfulness and placebo treatments on hearing improvement. More specifically, the researchers will be investigating whether the following variables impact the effectiveness of placebo treatment such as: mindfulness, and attention to variability. Extant research has found the effectiveness of psychological treatment in multiple domains, and the researchers look to further investigate this success in the domain of hearing symptom sensations.

Detailed Description

The placebo effect, described as "psychological or physiological responses attributed to expectations of an inert substance or procedure, has been demonstrated to have powerful effects in multiple instances (Colloca \& Benedetti, 2005). Although research on the placebo effect is prolific, the mechanisms involved can vary based on the context and have been difficult to research with consistent approaches and results (Brown et al., 2013; Holmes et al., 2018). Some researchers have found that the mere perception of a treatment as "new" is enough to elicit a placebo effect, while others have found that the key mechanism may be attention to symptoms - nevertheless, "little evidence exists on the precise mechanisms through which psychological treatments actually work" (Brown et al., 2013; Holmes et al., 2018). Earlier work suggests the potential for psychological treatments for hearing loss or other forms of hearing disability, including coping techniques (Scott et al, 2009). This study aims to extend the mind-body unity theory as suggested by Dawes et al. (2013) who found in two successive studies that there is a reliable placebo effect in hearing-aid trials. While the objective of these studies was to encourage double-blind methodology (to optimize results), these results suggest that such effects can optimize outcomes and as the audiology field does not typically consider placebo effects. it suggests that hearing improvements can be impacted by (positive) expectations in a "general" sense (not a specific type of hearing aid but simply a "new technology" hearing aid). While this will be of great use clinically in double blind trials, it suggests that the use of a psychological construct, specifically the Langerian attention to variability construct, can function to encourage a placebo effect or a clinical response by encouraging a sense of personal control over the symptoms of the hearing loss. In this study, researchers will look to further investigate one potential mechanism important to the placebo effect - attention to variability.

Registry
clinicaltrials.gov
Start Date
November 1, 2021
End Date
March 1, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ellen Langer

Professor

Harvard University

Eligibility Criteria

Inclusion Criteria

  • Between 18 and 80 years of age
  • Eyesight with corrective lenses sufficient enough to read and respond to emails
  • Owns or has access to and is familiar with using a smartphone and/or desk top/laptop with a cellular data plan and email host
  • Able to receive and respond to text messages and emails
  • Able to and access to watch, listen to and operate on a phone or computer a video or recording
  • English speaking and reading at 8th grade level
  • Self-Perceived mild to moderate hearing problem with onset after age 18 (adult onset)

Exclusion Criteria

  • Under age 18 or over age 80
  • Unable to read and respond to texts or emails
  • No Smartphone or desktop/laptop access
  • Hearing loss onset prior to age 18
  • Co-morbid conditions such as cancer, diabetes, cardiovascular disease diagnosed and under treatment in the past 6 months
  • Pregnancy

Outcomes

Primary Outcomes

Hearing Change - subjective preferred volume

Time Frame: 5 minutes daily for 6 days

Participants will be told to wear the hearing device and listen to a brief audio (ballad of under 3 minutes) twice a day daily for 6 days.The survey will ask them to listen to the audio and record the volume level that they used at the beginning and at the end, and then answer a few questions after. The change in participants subjective preferred volume over the course of the week , compared to T1 at the beginning of the week, will represent hearing change.

Secondary Outcomes

  • Langer Mindfulness Scale,14-Item scale(5 minutes)
  • Hearing Handicap Inventory for Adults- Screening (HHIA-S)(5 minutes)
  • Perceived Stress Scale (PSS)(5 minutes)
  • Hearing Handicap Inventory for Elderly- Screening (HHIE-S)(5 minutes)

Study Sites (1)

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