Response to Periodontal Therapy in a Chronic Kidney Disease Population
- Conditions
- Chronic Kidney Disease Stage 5Periodontal Disease
- Interventions
- Procedure: Non Surgical Periodontal Therapy
- Registration Number
- NCT03525457
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Brief Summary
This study will evaluate periodontal and systemic parameters of a cohort of chronic kidney disease (stage 5) patients, before and three months after non-surgical periodontal treatment. It does not consider a control group.
- Detailed Description
Dental biofilm is a source of inflammation and infection of periodontal tissues. In the last 20 years the interaction between periodontal infections and systemic conditions has been largely studied, suggesting that the inflammation caused in the periodontal tissues could cause a response in other parts of the body.
Recent studies suggest that there could be an association between periodontal disease and chronic kidney disease.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 65
- Chronic kidney disease patients in Stage 5 (candidates to renal transplant)
- Younger than 18 year old.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Experimental Non Surgical Periodontal Therapy Non surgical periodontal therapy
- Primary Outcome Measures
Name Time Method Change in Clinical Attachment Level (CAL) 3 months Change from baseline CAL (in mm) at three months
- Secondary Outcome Measures
Name Time Method Change in Bleeding on probing (BOP) 3 months Change from baseline BOP (%) at three months
Trial Locations
- Locations (1)
Clínica Odontológica Docente UC
🇨🇱Santiago, Región Metropolitana, Chile