Response to Non Surgical Periodontal Therapy in a Chronic Kidney Disease Population Candidates to Kidney Transplant
试验速览
- 阶段
- 不适用
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Change in Clinical Attachment Level (CAL)
研究概览
简要总结
This study will evaluate periodontal and systemic parameters of a cohort of chronic kidney disease (stage 5) patients, before and three months after non-surgical periodontal treatment. It does not consider a control group.
详细描述
Dental biofilm is a source of inflammation and infection of periodontal tissues. In the last 20 years the interaction between periodontal infections and systemic conditions has been largely studied, suggesting that the inflammation caused in the periodontal tissues could cause a response in other parts of the body.
Recent studies suggest that there could be an association between periodontal disease and chronic kidney disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic kidney disease patients in Stage 5 (candidates to renal transplant)
排除标准
- •Younger than 18 year old.
研究组 & 干预措施
Experimental
Non surgical periodontal therapy
干预措施: Non Surgical Periodontal Therapy (Procedure)
结局指标
主要结局
Change in Clinical Attachment Level (CAL)
时间窗: 3 months
Change from baseline CAL (in mm) at three months
次要结局
- Change in Bleeding on probing (BOP)(3 months)
研究者
Maité Souyet
DDS, MsC
Pontificia Universidad Catolica de Chile