Effects of lowering blood glucose on T Lymphocyte activation in human adipose tissue

niversity of Bath (UK)0 个研究点目标入组 22 人开始时间: 2013年12月20日最近更新: 2017年2月20日

适应症

试验速览

暂无简介。

•1. Male or postmenopausal* female
•2. Aged between 45 to 65years
•3. Waist circumference >94cm (males) or >80cm (females)
•4. Weight stable for more than 3 months (no change in weight +/- 3%)
•Non-smoker
•Group 1 participants will be overweight with 'normal glucose tolerance' as defined by 2h oral glucose tolerance test (blood glucose <7.8 mmol/L at 2h post 75g glucose drink)
•Group 2 participants will be overweight with 'impaired glucose tolerance' (blood glucose >7.8 mmol/L but <11.1mmol/L at 2h post 75g glucose drink)
•*postmenopausal defined as no menstruation for at least 1 year (Witteman, Grobbee et al. 1989).; Target Gender: Male & Female; Upper Age Limit 65 years ; Lower Age Limit 45 years

•1. Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
•2. Taking medications that may influence lipid or carbohydrate metabolism or immune system function
•3. Perform >150minutes/week moderate intensity exercise

发起方

niversity of Bath (UK)