Thrombin Generation and Gestational Outcome

Completed

• Conditions: Thrombophilia

• Registration Number: NCT02139670
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

In total 120 pregnant women's with history of recurrent miscarriages, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). The relation between pregnancy outcome and thrombin measurements will be determined

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-08-26
• Study Start: 2013-10
• Study First Submitted QC: 2014-05-13
• Study First Posted: 2014-05-15
• Primary Completion: 2016-09
• Study Completion: 2017-12
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-28
• Last Update Posted: 2018-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 29

Inclusion Criteria

• age > 18
• signed inform consent
• first trimester
• two early miscarriages(before week 10) or one later abortions (after week 10)

Exclusion Criteria

• Chronic treatment with aspirin or other anticoagulants

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pregnancy outcome	2 years

Trial Locations

Locations (1)

Haemek medical center; 🇮🇱 Afula, Israel