To identify blood based biomarker to predict lupus flare using molecular and protein marker
Not Applicable
- Conditions
- Health Condition 1: M048- Other autoinflammatory syndromes
- Registration Number
- CTRI/2024/07/071185
- Lead Sponsor
- Indian Rheumatology Association
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
SLE patients with mild or severe flare
Patients conformed to the SLE classification criteria by the 2019 EULAR/ACR classification
Female or male above 18 years
Exclusion Criteria
Pregnant women
Malignant Patients
Patients with other autoimmune disease
Patients with comorbidities
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To develop miRNA characterization and blood proteomics profiles in lupus at different disease activities. <br/ ><br>2. The targeted miRNA-protein pathway will be used to develop novel targeted therapy for lupusTimepoint: 12 months
- Secondary Outcome Measures
Name Time Method Identifying specific miRNA and protein-specific pathways from the blood cell will help in screening and early diagnosis, as well as a novel way to monitor precision therapy.Timepoint: 12 months