NCT03834259已完成不适用
The Effects of Keeping the Patient in a Sitting Position for One Minute After Spinal Anesthesia on Hypotension, Nausea-vomiting and Ephedrine Consumption
Umraniye Education and Research Hospital0 个研究点目标入组 214 人开始时间: 2017年1月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 214
- 主要终点
- systolic arterial hypotension
研究概览
简要总结
The aim of this study was to examine the effect of keeping the patient in a sitting position for 1 minute after spinal anaesthesia in elective caesarean operations, primarily on the formation of hypotension and secondarily on nausea-vomiting, the need for ephedrine and the block characteristics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •aged 18 - 45 years,
- •ASA physical status
- •BMI of 25-30
- •who were undergoing elective CS
排除标准
- •vertebral anomaly,
- •peripheral vascular disease,
- •cardiovascular or psychiatric disorder,
- •severe anemia,
- •coagulopathy
- •infection in the intervention region
研究组 & 干预措施
Group 1
Active Comparator
12.5 mg 0.5% hyperbaric bupivacaine
干预措施: sitting position (Procedure)
Group 2
Active Comparator
10 mg 0.5% hyperbaric bupivacaine
干预措施: supine position (Procedure)
Group 3
Active Comparator
12.5 mg 0.5% hyperbaric bupivacaine
干预措施: supine position (Procedure)
结局指标
主要结局
systolic arterial hypotension
时间窗: every 3 minutes until the delivery and every 5 minutes until the end of surgery
reduction of \>25% in the basal systolic arterial pressure
次要结局
- surgeon and patient satisfaction(24 hours after spinal block)
- motor block(24 hours after spinal block)
- sensory block(10 minutes after spinal block)
- amount of ephedrine(1 hour after spinal block)
- ephedrine requirement time(1 hour after spinal block)
研究者
Gulsah Karaoren
associate professor
Umraniye Education and Research Hospital
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