effects of intra-ovarian injection of autologous platelet rich plasma

Not Applicable

• Conditions: diminished ovarian reserve.; infertility due to diminished ovarian reserve; N97.0

• Registration Number: IRCT20101227005485N9
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 22

Inclusion Criteria

Antimullerian hormone(AMH) less than 1.1
number of antral follicles less than 5-7
history of cycle cancellation due to insufficient follicular growth
history of cycle cancellation due to less than 3 oocytes obtained
willingness to cooperate
Ages between 30 and 43 years

Exclusion Criteria

Immunoglobulin A deficiency
genital or non-genital cancers
treatment with anticoagulants
ovarian failure due to chromosomal abnormality
severe pelvic adhesion
non-acceptance or cooperation of the patient

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of oocytes obtained. Timepoint: Immediately after ovarian puncture before and 2 months after injection of platelet-rich plasma (PRP). Method of measurement: Under a microscope by an embryologist.;Follicular Stimulating Hormone (FSH) and Luteinizing Hormone (LH) day two or three of menstruation. Timepoint: Cycle before and 2 months after injection of platelet-rich plasma. Method of measurement: electrochemiluminescence.;Antimulerian hormone. Timepoint: Cycle before and 2 months after injection of platelet-rich plasma. Method of measurement: electrochemiluminescence.;Comparison of serum estradiol levels on the day of ovulation triggering. Timepoint: Cycle before and 2 months after injection of platelet-rich plasma. Method of measurement: electrochemiluminescence.

Secondary Outcome Measures

Name	Time	Method
umber of 4 to 8 cells embryos. Timepoint: 2 to 3 days. Method of measurement: With a microscope by an embryologist.