Perioperative Heart Rate Variability Analysis in Realtime: Detection of Cardiovascular and Autonomic Dysfunction
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Medical University of Vienna
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- Heart rate variability
Study Overview
Brief Summary
This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent to surgical operations performed under general anesthesia. Through retrospective analysis of patients' heart rate variability (HRV), in concert with the other abovementioned parameters, the investigators seek to forward the development of novel mathematical models and tools for on-line detection of cardiovascular and autonomic dysfunction in the perioperative setting.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing non-cardiac surgery under general anesthesia
- •Patients aged 18-80 years
- •Patients who are capable of giving informed consent
Exclusion Criteria
- •Patients <18 or >80 years of age
- •Patients with an active cardiac pace maker
- •Patients with an absent sinus rhythm in ECG
- •Patients presenting with a preexisting arrhythmia
- •Patients requiring postoperative ICU therapy
- •Patients with pheochromocytoma
Outcomes
Primary Outcomes
Heart rate variability
Time Frame: During and immediately subsequent to surgery performed under general anesthesia
The analysis of heart rate variability (HRV) has been used to assess autonomic nervous system responses to therapeutic interventions, and to quantify risk in a wide variety of both cardiac and non-cardiac disorders when combined with other diagnostic tests - though HRV analysis has seen its greatest cardiologic use in post-myocardial infarction risk stratification and in assessing risk for arrhythmic events. HRV analysis has become widespread and relatively simple to perform - however, until now, these analyses have not been performed in detail in the perioperative period.
Secondary Outcomes
No secondary outcomes reported
Investigators
Adam Joel Bukaty
Dr. Adam Joel Bukaty
Medical University of Vienna