Novel Equation for Estimating Resting Energy Expenditure in Dialysis Patients

Completed

• Conditions: Peritoneal Dialysis; Resting Energy Expenditure; Equation

• Registration Number: NCT04947839
• Lead Sponsor: Peking University First Hospital

Brief Summary

The energy and nutrition states are closely associated with dialysis patients' complications and outcomes. To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations do not focus on and applicable to peritoneal dialysis patients, so we aim to develop and validate an equation for estimating resting energy expenditure in peritoneal patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-18
• Study First Submitted: 2021-06-24
• Study First Submitted QC: 2021-06-24
• Study First Posted: 2021-07-01
• Primary Completion: 2022-06-28
• Study Completion: 2022-07-08
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-27
• Last Update Posted: 2022-09-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Peritoneal dialysis patients and hemodialysis patients
• Dialysis length >3 months
• >18 years old
• Consented to participate in all aspects of the study

Exclusion Criteria

• Acute complications to hospitalization 1 month prior to the study;
• Acute or chronic infections, cancer, and other wasting diseases in the past year;
• Thyroid dysfunction;
• Acute onset of podagra; Musculoskeletal diseases;
• Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);
• History of hormonal drug use;
• During pregnancy or lactation;
• Can not maintain posture and complete the REE test.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Novel equation development	March 18, 2021 to October 30, 2021	Developed equation for estimating resting energy expenditure in peritoneal dialysis patients
Novel equation validation	October 30, 2021 to December 30, 2021	Validate the novel equation with resting energy expenditure obtained by indirect calorimetry (IC).

Trial Locations

Locations (2)

Peking Haidian Hospital; 🇨🇳 Beijing, China

Peking University First Hospital; 🇨🇳 Beijing, Beijing, China